COVID Long Hauler Discussion with Dr. Bruce Patterson, Dr. Yo, & Dr. Bream Notes (4.11.21)
All notes below are thoughts expressed during a discussion with Dr. Bruce Patterson. Dr. Yo, and Dr. Bream on 4.11.21. Please consult a physician before acting upon any of the information presented below. Notes may be incomplete.
- IL-6 and IL-8 cause muscle and joint pain
- Some people 3 months out may have active COVID with rna – decreased CD8
- CD4 low with hiv
- CD8 low with COVID — single digits, but should be about 30
- 25% of Long Haulers still have low CD8%
- 4,500 patients registered at http://www.covidlonghaulers.com and are being tested
- Dr. P has treated 100+ Long Haulers
- Incredible immune response seen in LHers
- Elevated Rantees (71% of time) – can happen in any organ
- Blocking CCR5 important in active COVID and for Long Haulers
- CCR5 also works for another reason (published — ???)
- Rantees is elevated in active COVID and LHers
- IL-2, IFN-y (antiviral immune responses) – low in novel COVID (because it’s new to body)
- LHers – high IL-2 (fatigue, burning, brain fog, almost anything) and IFN-y
- VEGF (fatigue) – most important brain fog marker
- 79% of LHers have elevated VEGF – possibly due to vasculitis, micro clots, damage to endothelium
- Ivermectin and steroids for IL-2 and VEGF
- One subject was 95% better with Maraviroc (went from a LHI of 11.4 to 1.3)
- 50% better with Ivermectin and same with Steroids
- 50/50 for Maraviroc as well
- Fluvox may help with brain fog and help with blood clots
- COVID protein found in LHers in a cell type that migrated from the brain to different parts of the body — easily passes BBB
- This cell type is mobilized by exercise (possibly why people feel worse after exercise, Dr. P has seen this happen time and time again with Long Haulers)
- This cell type expresses CCR5
- Could inhibit these cells with LL or Maraviroc
- $360 for blood panel Dr. P offers at his website above — could be reimbursed by insurance
- 14 markers tested, plus severity score, LHI, and put in algorithm
- Rantees attracts macrophages and T cells (like a bee to honey)
- CCR5 regulated by cytokines
- CCR5 expression on immune cells going crazy because of cytokines
- Women have better immune systems than men, higher autoimmune rates
- Dr Yo loves Dr. P
- All advocacy groups led by women (Not mine Dr. P)
